REZOLV3R is a randomised, double-blind, multi-centre trial treating symptomatic patients with recurrent malignant ascites suitable for paracentesis and a paracentesis-free interval of 28 days or less. The aim of the … Continue reading REZOLV3R: Intraperitoneal bevacizumab for recurrent malignant ascites in chemotherapy resistant solid tumours: a randomised trial
CONDITION: Cancer
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
Australian researchers are testing a potential new treatment for obesity and weight-related comorbidities in adolescents. This is a 76 week study and may include up to 23 visits. Your adolescent … Continue reading Volunteers Needed for Adolescent Obesity Study
CONDITION: Diet and Nutrition
GENDER: All
AGE GROUP: 12 to 17 years
TRIAL STATUS: Recruiting
The objective of ASPIRE-AF is to assess the feasibility of a randomized controlled trial of non-vitamin K oral anticoagulants versus usual care in patients with perioperative atrial fibrillation (AF) after … Continue reading Anticoagulation for Stroke Prevention In patients with Recent Episodes of Perioperative Atrial Fibrillation after noncardiac surgery
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 55 and above
TRIAL STATUS: Recruiting
This international, multicentre, pragmatic, double-blind, placebo-controlled, randomised trial of TxA versus placebo will enrol 3,300 patients throughout Australia and internationally. This is an effectiveness trial – some elements of the … Continue reading Tranexamic acid to Reduce Infection after Gastrointestinal Surgery: the TRIGS Trial
CONDITION: Anaesthesiology
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
Australian researchers are testing a potential new treatment for chronic skin wounds. This is a 10 week study with at least 8 separate visits. You will be treated at no … Continue reading Volunteers Needed for Chronic Skin Wound Study
CONDITION: Skin
GENDER: All
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
This study aims to test a potential new treatment for IBS using a Gastrointestinal Reprogramming Product (GaRP) that has been designed by Anatara to address the key underlying factors associated … Continue reading Dose Determination and Efficacy Evaluation of the Gastrointestinal ReProgramming (GaRP) Dietary supplement in IBS patients: A Randomized, Double-blind, Placebo-controlled clinical trial
CONDITION: Oral and Gastrointestinal
GENDER: Both males and females
AGE GROUP: 18 to 65 years
TRIAL STATUS: Not yet recruiting
Australian researchers are testing a potential new treatment for atopic dermatitis (eczema) in children. This is a 36 week study with at least 12 separate visits. Your child will be … Continue reading Volunteers Needed for Atopic Dermatitis (Eczema) Study
CONDITION: Skin
GENDER: All
AGE GROUP: 6 to 17 years
TRIAL STATUS: Recruiting
Aims: to document the efficacy and safety outcomes of SCS in persons with chronic, chemotherapy-induced peripheral neuropathy Types of chemotherapy: Taxotere, Oxaliplatin, Paclitaxel Primary outcome measure: % responder rate at … Continue reading The purpose of this study is to evaluate the effectiveness of High Frequency (10kHz) Spinal Cord Stimulation in patients with chronic Chemotherapy-Induced Peripheral Neuropathy
CONDITION: Cancer
GENDER: Both males and females
AGE GROUP: 18 to 100 years
TRIAL STATUS: Recruiting
What is the study about? Are you interested in finding out how our microbiome (the DNA of all the ‘bugs’ that live on us and in us) can impact on … Continue reading The MothersBabies Study
CONDITION: Reproductive Health and Childbirth
GENDER: Females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
Patients presenting to the emergency department with acute ischemic stroke, who are are eligible for standard intravenous thrombolytic therapy within 4.5 hours of stroke onset will be assessed for major … Continue reading EXTEND-IA DNase: Improving early reperfusion with adjuvant dornase alfa in large vessel ischemic stroke
CONDITION: Stroke
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
ARE YOU AGED BETWEEN 50 and 80 YEARS OLD? ARE YOU FULLY VACCINATED AGAINST COVID-19 (with or without a booster)? You may qualify* to take part in a trial for … Continue reading COVID-19 and influenza combination vaccine
CONDITION: Other
GENDER: Both males and females
AGE GROUP: 50 to 80 years
TRIAL STATUS: Completed
Patients presenting to the emergency department with an acute ischemic stroke due to a large vessel occlusion eligible for thrombectomy and target mismatch on computed tomography perfusion imaging within 24 … Continue reading Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion (ETERNAL-LVO)
CONDITION: Stroke
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Completed
One stick of sugar-free peppermint-flavoured chewing gum (Wrigley’s Extra Sugarfree Gum, Wrigley Company) in the event of nausea, retching and/or vomiting occurring in the post anaesthesia care unit (PACU) after … Continue reading CHEWY Trial: A multi-centre randomized non-inferiority trial of chewing gum versus ondansetron to treat postoperative nausea and vomiting in female patients after breast or laparoscopic surgery.
CONDITION: Anaesthesiology
GENDER: Females
AGE GROUP: 12 and above
TRIAL STATUS: Completed
VAPOR-C is a randomised study of the impact of IV versus inhaled anaesthesia (propofol versus sevoflurane) and lidocaine versus no lidocaine on duration of disease free survival inpatients with either … Continue reading Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: The VAPOR-C Trial
CONDITION: Anaesthesiology
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
About this clinical trial: Wesley Medical Research is seeking research participants for a study evaluating the safety and tolerability of an investigational drug for Amyotrophic lateral sclerosis (ALS) and how … Continue reading A clinical study in individuals with Amyotrophic Lateral Sclerosis (ALS)
CONDITION: Neurological
GENDER: Both males and females
AGE GROUP: 18 to 75 years
TRIAL STATUS: Recruiting
Australian researchers are testing a new treatment for non-alcoholic steatohepatitis (NASH), an advanced form of non-alcoholic fatty liver disease (NAFLD). A new medication is to be taken orally 3 times … Continue reading Do you have non-alcoholic steatohepatitis (NASH)?
CONDITION: Inflammatory and Immune System
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Active, not recruiting
Have you been recently diagnosed with uncomplicated urogenital Gonorrhoea? Or do you have urogenital discharge and haven’t been treated yet? A new treatment might be available to you.
CONDITION: Reproductive Health and Childbirth
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
If you: Are a female between 18-45 years old Are symptomatic of BV Have not been treated with Antibiotics yet You may be eligible to take part in a research … Continue reading Bacterial Vaginosis
CONDITION: Other
GENDER: Females
AGE GROUP: 18 to 45 years
TRIAL STATUS: Recruiting
*** This trial is conducted online *** Psychological distress in people diagnosed with cancer is common and can have a number of negative consequences for affected people, including a reduced … Continue reading ONLINE: Yoga and mental health in cancer study
CONDITION: Mental Health
GENDER: Females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
Treating female patients with cervical squamous intraepithelial lesions (SIL), including both low grade and high grade lesions
CONDITION: Other
GENDER: Females
AGE GROUP: 25 to 55 years
TRIAL STATUS: Recruiting
SLT for Vascular Dementia Vascular dementia (VaD) is the second major cause of dementia accounting for 15-20 per cent of all dementia cases. VaD is an acquired cognitive impairment due … Continue reading Clinical trial of Sailuotong (SLT) for Vascular Dementia or Alzheimer’s Disease with evidence of cerebrovascular disease
CONDITION: Neurological
GENDER: Both males and females
AGE GROUP: 40 and above
TRIAL STATUS: Active, not recruiting
Project Title: Role of Sympathetic Activation in Ischemia Reperfusion Injury The aim of the study is to investigate the effectiveness of remote ischemic preconditioning (RIPC) in healthy male individuals. … Continue reading RIPC
CONDITION: Cardiovascular
GENDER: Males
AGE GROUP: 60 to 75 years
TRIAL STATUS: Recruiting
Project Title: Multi-Organ Denervation to Reduce Sympathetic Drive The purpose of this research study is to evaluate the safety of liver denervation, kidney denervation and a combination of both … Continue reading MODUS
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 22 to 70 years
TRIAL STATUS: Recruiting
Project Title: Global Clinical Study of Renal Denervation with the Symplicity SPYRALTM multi-electrode renal denervation system in Patients with Uncontrolled Hypertension on Standard Medical Therapy In some individuals with hypertension, … Continue reading SPYRAL HTN-ON-MED Study
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 20 to 80 years
TRIAL STATUS: Recruiting
An Australian researcher is testing an investigational product (Hidracare). In this study, we are trying to find out if Hidracare solution, a salt mixture, could improve the skin condition Hidradentitis … Continue reading Hidradenitis Suppurativa (Acne Inversa) Clinical Trial
CONDITION: Skin
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Completed
Project Title: The Role of Neuroinflammation in Hypertension – Minocycline for Resitant for Hypertension: A Randomised, double-blind, placebo-controlled trial The objective of this study is to establish whether or … Continue reading MINIHT
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 45 to 65 years
TRIAL STATUS: Recruiting
Project Title: Effects of SGLT-2 inhibition on Sympathetic Nervous System Activity in Humans This research study aims to assess whether Jardiance® (otherwise known as Empagliflozin), a medication approved for … Continue reading EMPA
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 25 to 65 years
TRIAL STATUS: Recruiting
Project Title: Sympathoinhibition as a preferred second line treatment of obesity related hypertension This research study aims to optimise the treatment of hypertension in individuals with obesity. It will compare … Continue reading Obesity Hypertension
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 25 to 70 years
TRIAL STATUS: Recruiting
CONDITION: Other
GENDER: Both males and females
AGE GROUP: 18 to 65 years
TRIAL STATUS: Recruiting
OVERVIEW The Holdsworth House Research team are currently looking for study participants who suffer from dust-related fibrotic respiratory diseases, such as coal workers pneumoconiosis (CWP, or Black Lung), silicosis, diffuse … Continue reading New trial into treatment of silicosis, asbestosis, black lung (or coal workers pneumoconiosis) and other dust diseases (the NiPS or Nintedanib in Pneumoconiosis Trial)
CONDITION: Respiratory
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting