Immune-mediated diseases are a broad category of conditions where the immune system functions abnormally and the immune response is inappropriate or excessive, resulting in harm to the body.
Autoimmune diseases occur when the immune system specifically fails to recognise the body’s own cells and tissues as “self,” leading it to mount an attack against them.
About the Study
Novatrials is seeking volunteers with rheumatoid arthritis, psoriatic arthritis, psoriasis, cutaneous lupus erythematosus, or atopic dermatitis (eczema) to join a clinical study of a potential new treatment for autoimmune or immune-mediated diseases. The study investigational drug is administered through a small subcutaneous injection.
The purposes of this study are to:
- Evaluate the safety and tolerability of the investigational drug
- Evaluate how the investigational drug gets into blood and is cleared from the body after administration
- Evaluate the effect of the investigational drug on the body and immune system
- Evaluate the effect of the investigational drug on disease symptoms
Eligibility Requirements
You may be eligible to join this study if you:
- Are aged 18 to 75 years
- Are not pregnant, breastfeeding or trying to conceive
- Have been diagnosed with one or more of the following conditions:
- rheumatoid arthritis
- psoriatic arthritis
- psoriasis
- cutaneous lupus erythematosus
- atopic dermatitis (eczema)
Full eligibility criteria will be discussed during phone screening.
What to Expect
- One phone pre-screening call (up to 30 minutes)
- Two in-clinic screening visits (within 28 days)
- One in-clinic treatment visit (approximately 4 hours)
- Eight in-clinic follow-up visits (within 16 weeks)
- One telephone call follow-up (approximately 1 hour)
Participant Benefits
You’ll contribute to advancing research for people with immune-related diseases around the world. Participants will be paid for their time and travel to attend visits at our Charlestown clinic. All study-related tests and treatments are provided at no cost to you.
