Bridging the Gap Between Participants and Clinical Trials

ISAAC Trial – Invasive Strep A: Defining the Role of Antibiotic Prophylaxis in Contact Management

CONDITION

Infection

GENDER

All

AGE GROUP

From 0

and above

STATUS

Recruiting

In the ISAAC trial, household contacts of iGAS (Invasive Group A Strep) cases will be invited to participate in the study. People who take part will be randomised to receive either: no antibiotics, a beta-lactam antibiotic or azithromycin. Participants will be asked to take throat swabs at baseline and day 14 to test for secondary iGAS.

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Approved By: Royal Melbourne Hospital HREC

Clinical Trial Registry Link: Click Here