NKT-203 – Treatment of Influenza-like Illnesses

a Phase 2 study looking at comparing the investigational product NKT versus placebo in the treatment of flu-like illness. Trial will run for 14 days and participants will attend the …

CONDITION: Respiratory

GENDER:

AGE GROUP: 18 to 64 years

TRIAL STATUS: Recruiting

A PHASE 2A, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, 16-WEEK STUDY EVALUATING THE SAFETY AND EFFICACY OF PF-06650833, PF-06700841, AND PF-06826647 IN ADULTS WITH MODERATE TO SEVERE HIDRADENITIS SUPPURATIVA

Inclusion criteria* To be eligible for enrolment in the study, all the following criteria must be met: 18-75 years of age Diagnosed (or recognisable symptoms consistent with a diagnosis) with …

CONDITION: Skin

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

A Multicenter, Randomized, Double-Blind Placebo-Controlled Phase 3 Study to Evaluate the Pharmacokinetics, Efficacy and Safety of BMS986165 in Adolescent Subjects with Moderate to Severe Plaque Psoriasis

This study will be a multi-center, randomized, double-blind, placebo controlled study, to evaluate the efficacy and safety of BMS-986165 in adolescent subjects ages 12 to < 18 years. This study …

CONDITION: Skin

GENDER: Both males and females

AGE GROUP: 12 to 17 years

TRIAL STATUS: Recruiting

Clinical trial of Sailuotong (SLT) for Vascular Dementia or Alzheimer’s Disease with evidence of cerebrovascular disease

SLT for Vascular Dementia Vascular dementia (VaD) is the second major cause of dementia accounting for 15-20 per cent of all dementia cases. VaD is an acquired cognitive impairment due …

CONDITION: Neurological

GENDER: Both males and females

AGE GROUP: 40 and above

TRIAL STATUS: Recruiting

RIPC

Project Title: Role of Sympathetic Activation in Ischemia Reperfusion Injury   The aim of the study is to investigate the effectiveness of remote ischemic preconditioning (RIPC) in healthy male individuals. …

CONDITION: Cardiovascular

GENDER: Males

AGE GROUP: 60 to 75 years

TRIAL STATUS: Recruiting

MODUS

Project Title: Multi-Organ Denervation to Reduce Sympathetic Drive   The purpose of this research study is to evaluate the safety of liver denervation, kidney denervation and a combination of both …

CONDITION: Cardiovascular

GENDER: Both males and females

AGE GROUP: 22 to 70 years

TRIAL STATUS: Recruiting

SPYRAL HTN-ON-MED Study

Project Title: Global Clinical Study of Renal Denervation with the Symplicity SPYRALTM multi-electrode renal denervation system in Patients with Uncontrolled Hypertension on Standard Medical Therapy In some individuals with hypertension, …

CONDITION: Cardiovascular

GENDER: Both males and females

AGE GROUP: 20 to 80 years

TRIAL STATUS: Recruiting

Hidradenitis Suppurativa (Acne Inversa) Clinical Trial

An Australian researcher is testing an investigational product (Hidracare). In this study, we are trying to find out if Hidracare solution, a salt mixture, could improve the skin condition Hidradentitis …

CONDITION: Skin

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

MINIHT

Project Title: The Role of Neuroinflammation in Hypertension – Minocycline for Resitant for Hypertension: A Randomised, double-blind, placebo-controlled trial   The objective of this study is to establish whether or …

CONDITION: Cardiovascular

GENDER: Both males and females

AGE GROUP: 45 to 65 years

TRIAL STATUS: Recruiting

EMPA

Project Title: Effects of SGLT-2 inhibition on Sympathetic Nervous System Activity in Humans   This research study aims to assess whether Jardiance® (otherwise known as Empagliflozin), a medication approved for …

CONDITION: Cardiovascular

GENDER: Both males and females

AGE GROUP: 25 to 65 years

TRIAL STATUS: Recruiting

Obesity Hypertension

Project Title: Sympathoinhibition as a preferred second line treatment of obesity related hypertension This research study aims to optimise the treatment of hypertension in individuals with obesity. It will compare …

CONDITION: Cardiovascular

GENDER: Both males and females

AGE GROUP: 25 to 65 years

TRIAL STATUS: Recruiting

SpineThera

SpineThera SALIENT

A double-Blind, Randomised, Placebo-Controlled, Parallel Group Phase 1/11, First-in-Human Study to Assess the Safety and Efficacy of Two Doses of SX600 Administered by Lumbosacral Transforaminal Epidural Injection in Patients with …

CONDITION: Other

GENDER: Both males and females

AGE GROUP: 18 to 65 years

TRIAL STATUS: Recruiting

New trial into treatment of silicosis, asbestosis, black lung (or coal workers pneumoconiosis) and other dust diseases (the NiPS or Nintedanib in Pneumoconiosis Trial)

OVERVIEW The Holdsworth House Research team are currently looking for study participants who suffer from dust-related fibrotic respiratory diseases, such as coal workers pneumoconiosis (CWP, or Black Lung), silicosis, diffuse …

CONDITION: Respiratory

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Do you experience UTIs?

OVERVIEW The Holdsworth House Research team are currently looking for study participants who suffer from Urinary Tract Infections (UTIs). We are investigating a new potential treatment for acute cystitis. The …

CONDITION: Renal and Urogenital

GENDER: Females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

HIV Research

OVERVIEW The Holdsworth House Research team are currently seeking volunteers for early stage research for HIV. There is no cost for study medication, and travel costs can be reimbursed. To …

CONDITION: Inflammatory and Immune System

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Gonorrhoea Clinical Study

Do you think you have Gonorrhoea? Gonorrhoea can cause serious health problems. A clinical research study for gonorrhoea may be an option for you. You may qualify for this no-cost …

CONDITION:

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Migraine Clinical Study

OVERVIEW The Holdsworth House Research team are currently looking for study participants who suffer from Migraines. The investigational product may reduce number of headache days. There is no cost for …

CONDITION: Neurological

GENDER: Both males and females

AGE GROUP: 18 to 70 years

TRIAL STATUS: Recruiting

Meningococcal Vaccine Study

Have you been vaccinated against Meningococcal Disease? The Holdsworth House Research team are currently recruiting for a study using investigational vaccines against Meningococcal Disease. If you are aged 18-25, have …

CONDITION: Infection

GENDER: Both males and females

AGE GROUP: 18 to 25 years

TRIAL STATUS: Recruiting

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Subjects with Moderate-to-Severe Atopic Dermatitis

This is a randomized, double-blind, placebo-controlled, multicenter, parallel-group study in adult and adolescent subjects with moderate-to-severe AD. Eligible subjects must have a documented history of inadequate response to topical AD …

CONDITION: Skin

GENDER: Both males and females

AGE GROUP: 12 and above

TRIAL STATUS: Active, not recruiting

Diabetes Type 2 Clinical Study

OVERVIEW The Holdsworth House Research team are currently seeking volunteers to trial a new possible Type 2 Diabetes therapy. We are seeking patients whose diabetes control could be improved. There …

CONDITION: Metabolic and Endocrine

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Herbal Medicine for Osteoarthritis of the Knee

Researchers at NICM Health Research Institute are seeking participants to join a clinical trial investigating the effectiveness and safety of an herbal medicine for the management of osteoarthritis of the …

CONDITION: Musculoskeletal

GENDER: Both males and females

AGE GROUP: 40 to 75 years

TRIAL STATUS: Closed: follow-up complete

Do You Have Frequent Cold Sore Flare Ups?

Research Centre: NICM Health Research Institute, Western Sydney University  Location: Online and via phone. No face to face contact is required with any member of the research team. Lead Doctor: …

CONDITION: Other

GENDER: Both males and females

AGE GROUP: 18 to 65 years

TRIAL STATUS: Recruiting

A randomized, double-blind, placebo-controlled, multiple-dose trial of the efficacy and safety of a sublingual glutathione wafer (RadianiX™) as a therapeutic skin health supplement.

Primary Objective: To determine the change in the following parameters following administration of RadianiX ™ Skin Melanin Index and Erythema Score Skin Hyperpigmentation Skin Elasticity Visual Skin Properties Skin Luminosity …

CONDITION: Skin

GENDER: Females

AGE GROUP: 30 to 65 years

TRIAL STATUS: Recruiting

CheckMate-901

CheckMate-901 is a phase 3 open-label clinical research study of drugs named nivolumab and ipilimumab. This study will test these drugs in adults with cancer of the bladder or upper …

CONDITION: Cancer

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Apollo

This is an open-label Phase 1/2 study to assess the safety and tolerability of combination PD-1 inhibitor (nivolumab) administered concomitantly with c-Met inhibitor (APL-101), to determine the recommended Phase 2 …

CONDITION: Cancer

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

The POLARIS Trial

POLARIS is a Phase 2 research trial testing a potential new treatment for BRAFV600-mutant positive melanoma that has spread to the brain. The new treatment is called encorafenib (Braftovi) + …

CONDITION: Cancer

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

EMERALD2

This is a Phase III, randomized, double-blind, placebo-controlled, multi-center, global study to assess the efficacy and safety of durvalumab in combination with bevacizumab or durvalumab monotherapy or placebo as adjuvant …

CONDITION: Cancer

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Psoriasis Trial Testing Investigational Cream

An Australian researcher is testing an investigational cream for plaque psoriasis. Participants will receive investigational cream (active study drug) or placebo. Investigational medication and study-related care will be provided at …

CONDITION: Skin

GENDER: Both males and females

AGE GROUP: 18 to 75 years

TRIAL STATUS: Recruiting

BEDROC

Depression affects millions.  Millions of people worldwide have major depressive disorder, the most commonly diagnosed form of depression. Depression is more than just sadness. It interferes with daily life and …

CONDITION: Mental Health

GENDER: Both males and females

AGE GROUP: 18 to 80 years

TRIAL STATUS: Recruiting

Standing Tall-Plus

The StandingTall team, has worked with over 500 community-dwelling older people since 2015, implementing a home-based balance exercise program delivered through a tablet computer. By embracing technology, we are providing …

CONDITION: Injuries and Accidents

GENDER: Both males and females

AGE GROUP: 65 and above

TRIAL STATUS: Recruiting