Novatrials is seeking adult volunteers who are obese or overweight and living with a weight related illness, to join a clinical study of a potential new oral treatment to improve weight management. For participants with type 2 diabetes, the study drug also aims to improve blood glucose levels.
In addition to the oral study drug, all participants will receive advice and support to develop or continue diet and physical activity that supports weight loss and healthy lifestyle.
Eligibility Requirements
You may be suitable to join this study if your BMI is:
- Over 30 or
- Over 25 and you have a weight related health condition (e.g. hypertension, prediabetes, dyslipidaemia, cardiovascular disease, obstructive sleep apnea) or
- Over 25 and you have type 2 diabetes
You can calculate your BMI here.
Other eligibility criteria include:
- Aged over 18 years
- Stable body weight for 3 months prior to screening
- No medication for weight loss within 90 days prior to the screening visit
- No previous or planned bariatric surgery or fitting of a weight loss device
Study Timeline & Clinic Visits
There is an initial visit to the clinic to determine your suitability for the trial. If all goes well, you will be invited to participate. This trial is structured in two key parts to ensure both thorough evaluation and long-term continuity of care:
Part 1: The Main Study (16 months total)
- Months 1 to 7: In-clinic visits occur once a month.
- Remainder of Main Study: In-clinic visits occur once every three months.
Part 2: The Long-Term Extension (16 months total)
Those who complete the main study will be invited to join the extension phase to continue their treatment journey:
- First 6 Months: Monthly clinic check-ins.
- Remainder of Extension: In-clinic visits occur once every three months.
