Project Title: Role of Sympathetic Activation in Ischemia Reperfusion Injury The aim of the study is to investigate the effectiveness of remote ischemic preconditioning (RIPC) in healthy male individuals. …
CONDITION: Cardiovascular
GENDER: Males
AGE GROUP: 60 to 75 years
TRIAL STATUS: Recruiting
Project Title: Multi-Organ Denervation to Reduce Sympathetic Drive The purpose of this research study is to evaluate the safety of liver denervation, kidney denervation and a combination of both …
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 22 to 70 years
TRIAL STATUS: Recruiting
Project Title: Global Clinical Study of Renal Denervation with the Symplicity SPYRALTM multi-electrode renal denervation system in Patients with Uncontrolled Hypertension on Standard Medical Therapy In some individuals with hypertension, …
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 20 to 80 years
TRIAL STATUS: Recruiting
An Australian researcher is testing an investigational product (Hidracare). In this study, we are trying to find out if Hidracare solution, a salt mixture, could improve the skin condition Hidradentitis …
CONDITION: Skin
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
Project Title: The Role of Neuroinflammation in Hypertension – Minocycline for Resitant for Hypertension: A Randomised, double-blind, placebo-controlled trial The objective of this study is to establish whether or …
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 45 to 65 years
TRIAL STATUS: Recruiting
Project Title: Effects of SGLT-2 inhibition on Sympathetic Nervous System Activity in Humans This research study aims to assess whether Jardiance® (otherwise known as Empagliflozin), a medication approved for …
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 25 to 65 years
TRIAL STATUS: Recruiting
Project Title: Sympathoinhibition as a preferred second line treatment of obesity related hypertension This research study aims to optimise the treatment of hypertension in individuals with obesity. It will compare …
CONDITION: Cardiovascular
GENDER: Both males and females
AGE GROUP: 25 to 65 years
TRIAL STATUS: Recruiting
A double-Blind, Randomised, Placebo-Controlled, Parallel Group Phase 1/11, First-in-Human Study to Assess the Safety and Efficacy of Two Doses of SX600 Administered by Lumbosacral Transforaminal Epidural Injection in Patients with …
CONDITION: Other
GENDER: Both males and females
AGE GROUP: 18 to 65 years
TRIAL STATUS: Recruiting
OVERVIEW The Holdsworth House Research team are currently looking for study participants who suffer from dust-related fibrotic respiratory diseases, such as coal workers pneumoconiosis (CWP, or Black Lung), silicosis, diffuse …
CONDITION: Respiratory
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
OVERVIEW The Holdsworth House Research team are currently looking for study participants who suffer from Urinary Tract Infections (UTIs). We are investigating a new potential treatment for acute cystitis. The …
CONDITION: Renal and Urogenital
GENDER: Females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
OVERVIEW The Holdsworth House Research team are currently seeking volunteers for early stage research for HIV. There is no cost for study medication, and travel costs can be reimbursed. To …
CONDITION: Inflammatory and Immune System
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
OVERVIEW The Holdsworth House Research team are currently looking for study participants who suffer from Migraines. The investigational product may reduce number of headache days. There is no cost for …
CONDITION: Neurological
GENDER: Both males and females
AGE GROUP: 18 to 70 years
TRIAL STATUS: Recruiting
Have you been vaccinated against Meningococcal Disease? The Holdsworth House Research team are currently recruiting for a study using investigational vaccines against Meningococcal Disease. If you are aged 18-25, have …
CONDITION: Infection
GENDER: Both males and females
AGE GROUP: 18 to 25 years
TRIAL STATUS: Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter, parallel-group study in adult and adolescent subjects with moderate-to-severe AD. Eligible subjects must have a documented history of inadequate response to topical AD …
CONDITION: Skin
GENDER: Both males and females
AGE GROUP: 12 and above
TRIAL STATUS: Recruiting
OVERVIEW The Holdsworth House Research team are currently seeking volunteers to trial a new possible Type 2 Diabetes therapy. We are seeking patients whose diabetes control could be improved. There …
CONDITION: Metabolic and Endocrine
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
Research Centre: NICM Health Research Institute, Western Sydney University Location: Online and via phone. No face to face contact is required with any member of the research team. Lead Doctor: …
CONDITION: Other
GENDER: Both males and females
AGE GROUP: 18 to 65 years
TRIAL STATUS: Recruiting
Primary Objective: To determine the change in the following parameters following administration of RadianiX ™ Skin Melanin Index and Erythema Score Skin Hyperpigmentation Skin Elasticity Visual Skin Properties Skin Luminosity …
CONDITION: Skin
GENDER: Females
AGE GROUP: 30 to 65 years
TRIAL STATUS: Recruiting
This is an open-label Phase 1/2 study to assess the safety and tolerability of combination PD-1 inhibitor (nivolumab) administered concomitantly with c-Met inhibitor (APL-101), to determine the recommended Phase 2 …
CONDITION: Cancer
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
POLARIS is a Phase 2 research trial testing a potential new treatment for BRAFV600-mutant positive melanoma that has spread to the brain. The new treatment is called encorafenib (Braftovi) + …
CONDITION: Cancer
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
This is a Phase III, randomized, double-blind, placebo-controlled, multi-center, global study to assess the efficacy and safety of durvalumab in combination with bevacizumab or durvalumab monotherapy or placebo as adjuvant …
CONDITION: Cancer
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting
An Australian researcher is testing an investigational cream for plaque psoriasis. Participants will receive investigational cream (active study drug) or placebo. Investigational medication and study-related care will be provided at …
CONDITION: Skin
GENDER: Both males and females
AGE GROUP: 18 to 75 years
TRIAL STATUS: Recruiting
Depression affects millions. Millions of people worldwide have major depressive disorder, the most commonly diagnosed form of depression. Depression is more than just sadness. It interferes with daily life and …
CONDITION: Mental Health
GENDER: Both males and females
AGE GROUP: 18 to 80 years
TRIAL STATUS: Recruiting
The StandingTall team, has worked with over 500 community-dwelling older people since 2015, implementing a home-based balance exercise program delivered through a tablet computer. By embracing technology, we are providing …
CONDITION: Injuries and Accidents
GENDER: Both males and females
AGE GROUP: 65 and above
TRIAL STATUS: Recruiting
Novatrials is seeking volunteers with moderate to severe Eczema (Atopic Dermatitis) to participate in a clinical trial under the supervision of Dermatologist Dr Lior Sagi, to test the safety and effectiveness …
CONDITION: Skin
GENDER: Both males and females
AGE GROUP: 18 to 65 years
TRIAL STATUS: Recruiting
The RESTORE clinical trial is a large scale research study in Australia exploring back pain treatments. We are trying to measure how effective existing treatments are for people with persistent …
CONDITION: Musculoskeletal
GENDER: Both males and females
AGE GROUP: 18 and above
TRIAL STATUS: Recruiting