Youth aged 12 to 17 with a history of eczema (atopic dermatitis) for at least one year, may qualify to participate in this study. Adolescents must have moderate to severe disease, involving 10% or more of their body. To be eligible, participants must also have a history of inadequate response to treatment with topical medications or for whom these topical medications are medically inadvisable.

Participants will receive investigational medication via injection (either active study drug or placebo). Study medication will be provided at no cost. Reimbursement for study-related expenses will be provided.

Study participation will last about 72 weeks and involve about 30 visits to the study clinic. In addition, 2 visits will occur by telephone.

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