I7P-MC-DSAF: Moderate to Severe Hidradenitis Suppurativa

A Phase 2b, Double-Blind, Placebo-Controlled Study to Evaluate Eltrekibart in Adult Participants with Moderate to Severe Hidradenitis Suppurativa

CONDITION: Skin

GENDER: All

AGE GROUP: 18 to 75 years

TRIAL STATUS: Active, not recruiting

GS-US-563-5926: Oral Weekly Islatravir/ Lenacapavir Regimen in People with HIV-1 Who are Virologically Suppressed on Standard of Care

A Phase 3 Randomized, Active-Controlled, Open-Label Study to Evaluate a Switch to an Oral Weekly Islatravir/ Lenacapavir Regimen in People with HIV-1 Who are Virologically Suppressed on Standard of Care

CONDITION: Other

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Active, not recruiting

GS-US-563-5925: People With HIV-1 Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir

A Phase 3, Randomized, Active-controlled, Double-blind Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV-1 Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir (B/F/TAF)

CONDITION: Other

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Active, not recruiting

A Phase III Multicenter, Open-Label, Randomized Study to Evaluate a Switch to MK-1439A in HIV-1-Infected Subjects Virologically Suppressed on a Regimen of a Ritonavir-boosted Protease Inhibitor and Two Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

CONDITION: Inflammatory and Immune System

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Completed

CIC-E-301

A Phase 3, Randomized, Observer-Blinded, Active-Controlled Study to Evaluate the Safety and Immunogenicity of a SARS‑CoV‑2 rS Nanoparticle and Trivalent Hemagglutinin Nanoparticle Influenza Combination Vaccine with Matrix-M™ Adjuvant and a …

CONDITION: Other

GENDER: All

AGE GROUP: 60 and above

TRIAL STATUS: Active, not recruiting

CPX101-Ⅱ-01 Obese Subjects without Diabetes Mellitus

A Randomized, Double-blind, Placebo-controlled, Parallel-group Multicenter Trial to Evaluate the Safety and Efficacy of CPX101 in Overweight and Obese Subjects without Diabetes Mellitus

CONDITION: Metabolic and Endocrine

GENDER: All

AGE GROUP: 18 to 75 years

TRIAL STATUS: Active, not recruiting

HB-PD-002: Panic Disorder

Efficacy and Safety of HB-1 for Panic Disorder: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

CONDITION: Mental Health

GENDER: All

AGE GROUP: 18 to 65 years

TRIAL STATUS: 

ABI-1179-101: Subjects with Recurrent Genital Herpes

A Phase 1a/1b, Blinded, Placebo-Controlled Study of the Safety, Tolerability and Pharmacokinetics of Single- and Multiple-Ascending Doses of ABI-5366 in Healthy Subjects and in Subjects who are Seropositive for HSV-2 …

CONDITION: Other

GENDER: All

AGE GROUP: 18 to 60 years

TRIAL STATUS: 

A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Antiretroviral Activity of MK-1439 in HIV-1 Infected Patients

CONDITION: Inflammatory and Immune System

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Completed

CONDITION: Infection

GENDER: Males

AGE GROUP: 18 to 50 years

TRIAL STATUS: Closed: follow-up complete

ABI-5366-101: Subjects with Recurrent Genital Herpes

A Phase 1a/1b, Blinded, Placebo-Controlled Study of the Safety, Tolerability and Pharmacokinetics of Single- and Multiple-Ascending Doses of ABI-5366 in Healthy Subjects and in Subjects who are Seropositive for HSV-2 …

CONDITION: Other

GENDER: All

AGE GROUP: 18 to 60 years

TRIAL STATUS: Recruiting

A Study Evaluating Efficacy and Safety of Gepotidacin Compared With Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea

This is a phase III, randomized, multicenter, open-label study which will be performed to evaluate efficacy and safety of oral Gepotidacin compared to intramuscular (IM) ceftriaxone plus oral azithromycin for the treatment …

CONDITION: Infection

GENDER: All

AGE GROUP: 12 and above

TRIAL STATUS: Completed

Control and Elimination Within Australia of Hepatitis C From People Living With HIV (CEASE)

A seven year plan of enhanced HCV monitoring, primary care–based workforce development, rapid scale-up of HCV treatment and public health policy action in HIV positive individuals within Australia.

CONDITION: Inflammatory and Immune System

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Completed

A Phase IIIb, Randomized, Multicenter, Parallel-group, Non-inferiority, Open-label Study Evaluating the Efficacy, Safety, and Tolerability of Long-acting Cabotegravir Plus Long-acting Rilpivirine Administered Every 8 Weeks or Every 4 Weeks in HIV-1-infected Adults Who Are Virologically Suppressed

This Antiretroviral Therapy as Long Acting Suppression every 2 Months (ATLAS-2M) study is designed to demonstrate the non-inferior antiviral activity and safety of CAB LA + RPV LA administered every …

CONDITION: Inflammatory and Immune System

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Active, not recruiting

GS-US-536-5939: Virologically Suppressed Adults With HIV-1 Infection

A Phase 2 Randomized, Open-label Study to Evaluate the Safety and Efficacy of Broadly Neutralizing Antibodies (bNAbs) GS-5423 and GS-2872 in Combination With the Capsid Inhibitor Lenacapavir as Long-Acting Treatment …

CONDITION: Other

GENDER: All

AGE GROUP: 18 to 65 years

TRIAL STATUS: Active, not recruiting

A Study to Evaluate Efficacy and Safety of Cabotegravir (CAB) Long Acting (LA) Plus (+) Rilpivirine (RPV) LA Versus BIKTARVY® (BIK) in Participants With Human Immunodeficiency Virus (HIV)-1 Who Are Virologically Suppressed (SOLAR)

A Phase IIIb, Randomized, Multicenter, Active-controlled, Parallel-group, Non-inferiority, Open-label Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine Administered Every Two Months From a Bictegravir/Emtricitabine/Tenofovir Alafenamide …

CONDITION: Inflammatory and Immune System

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Completed

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy (ARTISTRY-2)

This study is being done to see how well a new HIV treatment works compared to current standard treatment. Researchers are testing a single tablet that combines bictegravir (BIC) and …

CONDITION: Inflammatory and Immune System

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Active, not recruiting

Phase 3 Trial of Bictegravir/Lenacapavir Fixed-Dose Combination (single daily pill) vs Standard HIV Therapy – ARTISTRY 1

This study is for people living with HIV whose treatment is already keeping the virus under control. Researchers are testing whether switching to new medicines, bictegravir and lenacapavir (together in …

CONDITION: Inflammatory and Immune System

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Active, not recruiting

A Phase 3 Study Evaluating the Safety and Effectiveness of Switching to a Once-Weekly Islatravir/Lenacapavir Regimen Compared to Continuing Standard Daily HIV Therapy in Virologically Suppressed Adults – ISLEND 2

This study is testing whether people with HIV whose virus is already well controlled can safely switch from their current daily HIV medicines to a new once-a-week pill (islatravir/lenacapavir).

CONDITION: Inflammatory and Immune System

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Active, not recruiting

A Phase 3 Study of Switching from Daily to Weekly Oral HIV Treatment – ISLEND 1

This is a large final-stage (Phase 3) clinical trial testing whether people living with HIV, who already have their virus under control on the standard daily HIV pill (Biktarvy® – …

CONDITION: Inflammatory and Immune System

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Active, not recruiting

REZOLV3R: Intraperitoneal bevacizumab for recurrent malignant ascites in chemotherapy resistant solid tumours: a randomised trial

REZOLV3R is a randomised, double-blind, multi-centre trial treating symptomatic patients with recurrent malignant ascites suitable for paracentesis and a paracentesis-free interval of 28 days or less. The aim of the …

CONDITION: Cancer

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Volunteers Needed for Adolescent Obesity Study

Australian researchers are testing a potential new treatment for obesity and weight-related comorbidities in adolescents. This is a 76 week study and may include up to 23 visits. Your adolescent …

CONDITION: Diet and Nutrition

GENDER: All

AGE GROUP: 12 to 17 years

TRIAL STATUS: Recruiting

Anticoagulation for Stroke Prevention In patients with Recent Episodes of Perioperative Atrial Fibrillation after noncardiac surgery

The objective of ASPIRE-AF is to assess the feasibility of a randomized controlled trial of non-vitamin K oral anticoagulants versus usual care in patients with perioperative atrial fibrillation (AF) after …

CONDITION: Cardiovascular

GENDER: Both males and females

AGE GROUP: 55 and above

TRIAL STATUS: Recruiting

Tranexamic acid to Reduce Infection after Gastrointestinal Surgery: the TRIGS Trial

This international, multicentre, pragmatic, double-blind, placebo-controlled, randomised trial of TxA versus placebo will enrol 3,300 patients throughout Australia and internationally. This is an effectiveness trial – some elements of the …

CONDITION: Anaesthesiology

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Volunteers Needed for Chronic Skin Wound Study

Australian researchers are testing a potential new treatment for chronic skin wounds. This is a 10 week study with at least 8 separate visits. You will be treated at no …

CONDITION: Skin

GENDER: All

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

Dose Determination and Efficacy Evaluation of the Gastrointestinal ReProgramming (GaRP) Dietary supplement in IBS patients: A Randomized, Double-blind, Placebo-controlled clinical trial

This study aims to test a potential new treatment for IBS using a Gastrointestinal Reprogramming Product (GaRP) that has been designed by Anatara to address the key underlying factors associated …

CONDITION: Oral and Gastrointestinal

GENDER: Both males and females

AGE GROUP: 18 to 65 years

TRIAL STATUS: Not yet recruiting

Volunteers Needed for Atopic Dermatitis (Eczema) Study

Australian researchers are testing a potential new treatment for atopic dermatitis (eczema) in children. This is a 36 week study with at least 12 separate visits. Your child will be …

CONDITION: Skin

GENDER: All

AGE GROUP: 6 to 17 years

TRIAL STATUS: Recruiting

The purpose of this study is to evaluate the effectiveness of High Frequency (10kHz) Spinal Cord Stimulation in patients with chronic Chemotherapy-Induced Peripheral Neuropathy

Aims: to document the efficacy and safety outcomes of SCS in persons with chronic, chemotherapy-induced peripheral neuropathy Types of chemotherapy: Taxotere, Oxaliplatin, Paclitaxel Primary outcome measure: % responder rate at …

CONDITION: Cancer

GENDER: Both males and females

AGE GROUP: 18 to 100 years

TRIAL STATUS: Recruiting

The MothersBabies Study

What is the study about? Are you interested in finding out how our microbiome (the DNA of all the ‘bugs’ that live on us and in us) can impact on …

CONDITION: Reproductive Health and Childbirth

GENDER: Females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting

EXTEND-IA DNase: Improving early reperfusion with adjuvant dornase alfa in large vessel ischemic stroke

Patients presenting to the emergency department with acute ischemic stroke, who are are eligible for standard intravenous thrombolytic therapy within 4.5 hours of stroke onset will be assessed for major …

CONDITION: Stroke

GENDER: Both males and females

AGE GROUP: 18 and above

TRIAL STATUS: Recruiting